2004Chinese Journal of Drug Application and MonitoringRequires access

A clinical observation on Tramadol in the treatment of chill after Epidural Anesthesia

Huang Qi-wen

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Abstract

Objective:To observe the clinical effect of tramadol in the treatment of chill after epidural anesthesia.Methods: 100 patients under going epidural anesthesia were divided into two groups randomly,50 patients in tramadol group( Ⅰ) were injected intravenously with 1% tramadol(diluted with normal saline) lmg/kg.50 patients in pethidine group(Ⅱ) were injected intravenously with 1% pethidine(diluted with normal saline)0.75mg/kg.The speed of the two injection was 30mL/min,After five minutes the patients who were still chilling were injected with midazolam 0.05mg/kg.Observe the effect and ADRs after one minute,three minutes and five minutes.Results: After one minute and five minutes the effect has no statistically difference(p0.05).However,after three minutes the effect of the tramadol group was obviously superior to that of the pethidine group(p0.05),and the complications of tramadol group were also less than pethidine group(p0.01).Conelusions: Tramadol displayed good effect in treatment of the chill after epidural anesthesia.

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Objective:To observe the clinical effect of tramadol in the treatment of chill after epidural anesthesia.Methods: 100 patients under going epidural anesthesia were divided into two groups randomly,50 patients in tramadol group( Ⅰ) were injected intravenously with 1% tramadol(diluted with normal saline) lmg/kg.50 patients in pethidine group(Ⅱ) were injected intravenously with 1% pethidine(diluted with normal saline)0.75mg/kg.The speed of the two injection was 30mL/min,After five minutes the patients who were still chilling were injected with midazolam 0.05mg/kg.Observe the effect and ADRs after one minute,three minutes and five minutes.Results: After one minute and five minutes the effect has no statistically difference(p0.05).However,after three minutes the effect of the tramadol group was obviously superior to that of the pethidine group(p0.05),and the complications of tramadol group were also less than pethidine group(p0.01).Conelusions: Tramadol displayed good effect in treatment of the chill after epidural anesthesia.

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Available abstract

Objective:To observe the clinical effect of tramadol in the treatment of chill after epidural anesthesia.Methods: 100 patients under going epidural anesthesia were divided into two groups randomly,50 patients in tramadol group( Ⅰ) were injected intravenously with 1% tramadol(diluted with normal saline) lmg/kg.50 patients in pethidine group(Ⅱ) were injected intravenously with 1% pethidine(diluted with normal saline)0.75mg/kg.The speed of the two injection was 30mL/min,After five minutes the patients who were still chilling were injected with midazolam 0.05mg/kg.Observe the effect and ADRs after one minute,three minutes and five minutes.Results: After one minute and five minutes the effect has no statistically difference(p0.05).However,after three minutes the effect of the tramadol group was obviously superior to that of the pethidine group(p0.05),and the complications of tramadol group were also less than pethidine group(p0.01).Conelusions: Tramadol displayed good effect in treatment of the chill after epidural anesthesia.

Key concepts: Tramadol, Pethidine, Medicine, Anesthesia, Midazolam, Saline, Physiological saline, Surgery

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