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2009•Journal of Practical Obstetrics and GynecologyRequires access

Perinatal Outcomes of Intrahepatic Cholestasis of Pregnancy:Analysis of 131 Cases

Zhixiong Mei

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Abstract

Objective:To explore the influence of early detection of meconium stained amnionic fluid and timely termination of pregnancy on perinatal outcomes of intrahepatic cholestasis of pregnancy(ICP).Methods: The clinical data of 131 cases of ICP were retrospectively analyzed.Results: Meconium passage was documented in 49 cases,6 of which were detected by amniocentesis,34 by induced rupture of membrane,4 by cesarean section,and 5 by spontaneous rupture of membrane.The rate of meconium-stained amniotic fluid was 37.4%,premature delivery 26.0%,and cesarean section 62.6%,all of which were significantly higher in ICP patients than in normal preg

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Objective:To explore the influence of early detection of meconium stained amnionic fluid and timely termination of pregnancy on perinatal outcomes of intrahepatic cholestasis of pregnancy(ICP).Methods: The clinical data of 131 cases of ICP were retrospectively analyzed.Results: Meconium passage was documented in 49 cases,6 of which were detected by amniocentesis,34 by induced rupture of membrane,4 by cesarean section,and 5 by spontaneous rupture of membrane.The rate of meconium-stained amniotic fluid was 37.4%,premature delivery 26.0%,and cesarean section 62.6%,all of which were significantly higher in ICP patients than in normal preg

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Available abstract

Objective:To explore the influence of early detection of meconium stained amnionic fluid and timely termination of pregnancy on perinatal outcomes of intrahepatic cholestasis of pregnancy(ICP).Methods: The clinical data of 131 cases of ICP were retrospectively analyzed.Results: Meconium passage was documented in 49 cases,6 of which were detected by amniocentesis,34 by induced rupture of membrane,4 by cesarean section,and 5 by spontaneous rupture of membrane.The rate of meconium-stained amniotic fluid was 37.4%,premature delivery 26.0%,and cesarean section 62.6%,all of which were significantly higher in ICP patients than in normal preg

Key concepts: Medicine, Cholestasis of pregnancy, Obstetrics, Amniotic fluid, Amniocentesis, Meconium, Pregnancy, Cholestasis

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