2008Nongyaoxue xuebaoRequires access

Synthesis and Fungicidal Activity of N-(Arylsulfonylaminoethyl)-1,6-caprolactam

WU Jing-ping

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Abstract

Nine novel N-(arylsulfonylaminoethyl)-1,6-caprolactams(3) were synthesized from cyclohexanone.Their structures were confirmed by IR,1H NMR,13C NMR and elemental analysis.The bioassay showed that they have fungicidal activity against 6 kinds of fungi.Especially,the fungicidal activity of compounds 3a,3b,3d and 3g against Cladosporium graminis may be matched with that of commercial fungicide chlorothalonil.The inhibition rate was larger than 90%.

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What this paper is about

Nine novel N-(arylsulfonylaminoethyl)-1,6-caprolactams(3) were synthesized from cyclohexanone.Their structures were confirmed by IR,1H NMR,13C NMR and elemental analysis.The bioassay showed that they have fungicidal activity against 6 kinds of fungi.Especially,the fungicidal activity of compounds 3a,3b,3d and 3g against Cladosporium graminis may be matched with that of commercial fungicide chlorothalonil.The inhibition rate was larger than 90%.

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Available abstract

Nine novel N-(arylsulfonylaminoethyl)-1,6-caprolactams(3) were synthesized from cyclohexanone.Their structures were confirmed by IR,1H NMR,13C NMR and elemental analysis.The bioassay showed that they have fungicidal activity against 6 kinds of fungi.Especially,the fungicidal activity of compounds 3a,3b,3d and 3g against Cladosporium graminis may be matched with that of commercial fungicide chlorothalonil.The inhibition rate was larger than 90%.

Key concepts: Fungicide, Chlorothalonil, Cyclohexanone, Bioassay, Chemistry, Carbon-13 NMR, Proton NMR, Cladosporium

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