Screening and identification of mimotopes for lipopolysaccharide conservative epitope from random phage display peptide library
Weiyan Wen, Qiangtao Han, Ning Fu
Abstract
Weiyan Wen, Qiangtao Han, Ning Fu
Abstract
To screen and identify the mimotopes for lipopolysaccharide (LPS) epitope, a random phage displayed dodecapeptide library was screened with a monoclonal antibody 2B4 specifically against LPS conservative epitope. The results demonstrate that the peptides screened with 2B4 antibody are mimotopes for LPS conservative epitope.
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To screen and identify the mimotopes for lipopolysaccharide (LPS) epitope, a random phage displayed dodecapeptide library was screened with a monoclonal antibody 2B4 specifically against LPS conservative epitope. The results demonstrate that the peptides screened with 2B4 antibody are mimotopes for LPS conservative epitope.
Key concepts: Mimotope, Epitope, Phage display, Monoclonal antibody, Peptide library, Epitope mapping, Antibody, Lipopolysaccharide