2012PubMedRequires access

[Progress in research of clinical applications of fascia lata allograft].

Dong Li, Xueying Chen, Yumin Zhang, Baoxing Li, Xusheng Wang, Naili Zhang, Shaoying Ma

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Abstract

OBJECTIVE: To find out the recent progress in research of clinical application of fascia lata allograft. METHODS: The domestic and international articles were reviewed to summarize the principal properties, processing techniques, and various uses of fascia lata allograft. RESULTS: Histologically fascia lata is composed of parallel and compact bundles of collagen fibers with few cells and immunologically it is low-antigenic. After varied tissue processing and storage techniques, fascia lata, as the scaffold only with the extracellular matrix, has been used in clinical practice and achieved good results, such as ophthalmology, urology, and orthopaedics. CONCLUSION: Because of these unique properites in repairing defects and reconstructing functions, fascia lata allograft, as a natural biomaterial, is promising to be used in more aspects with the development of the biomedical techniques.

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What this paper is about

OBJECTIVE: To find out the recent progress in research of clinical application of fascia lata allograft. METHODS: The domestic and international articles were reviewed to summarize the principal properties, processing techniques, and various uses of fascia lata allograft. RESULTS: Histologically fascia lata is composed of parallel and compact bundles of collagen fibers with few cells and immunologically it is low-antigenic. After varied tissue processing and storage techniques, fascia lata, as the scaffold only with the extracellular matrix, has been used in clinical practice and achieved good results, such as ophthalmology, urology, and orthopaedics. CONCLUSION: Because of these unique properites in repairing defects and reconstructing functions, fascia lata allograft, as a natural biomaterial, is promising to be used in more aspects with the development of the biomedical techniques.

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Available abstract

OBJECTIVE: To find out the recent progress in research of clinical application of fascia lata allograft. METHODS: The domestic and international articles were reviewed to summarize the principal properties, processing techniques, and various uses of fascia lata allograft. RESULTS: Histologically fascia lata is composed of parallel and compact bundles of collagen fibers with few cells and immunologically it is low-antigenic. After varied tissue processing and storage techniques, fascia lata, as the scaffold only with the extracellular matrix, has been used in clinical practice and achieved good results, such as ophthalmology, urology, and orthopaedics. CONCLUSION: Because of these unique properites in repairing defects and reconstructing functions, fascia lata allograft, as a natural biomaterial, is promising to be used in more aspects with the development of the biomedical techniques.

Key concepts: Fascia lata, Extracellular matrix, Medicine, Transplantation, Fascia, Anatomy, Surgery, Biology

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