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2003•Progress in Veterinary MedicineRequires access

Research Survey of Enterotoxin in Enterotoxigenic Escherichia coli

Zhang Xue

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Abstract

The text analysed biological characteristics,molecular mechanisms and application of heat labile(LT)and heat stable(ST)enterotoxin.First of all,different mutants of LT that have been demonstrated as mucosal adjuvants were constructed by site directed mutagenesis and proved to be the excellent candidates of CT.Next,genetically engineered vaccine of fused LT and ST,which was beneficial to preventing and treating diarrhea, was constructed .These results give a base for further research on enterotoxin in ETEC.

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What this paper is about

The text analysed biological characteristics,molecular mechanisms and application of heat labile(LT)and heat stable(ST)enterotoxin.First of all,different mutants of LT that have been demonstrated as mucosal adjuvants were constructed by site directed mutagenesis and proved to be the excellent candidates of CT.Next,genetically engineered vaccine of fused LT and ST,which was beneficial to preventing and treating diarrhea, was constructed .These results give a base for further research on enterotoxin in ETEC.

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Available abstract

The text analysed biological characteristics,molecular mechanisms and application of heat labile(LT)and heat stable(ST)enterotoxin.First of all,different mutants of LT that have been demonstrated as mucosal adjuvants were constructed by site directed mutagenesis and proved to be the excellent candidates of CT.Next,genetically engineered vaccine of fused LT and ST,which was beneficial to preventing and treating diarrhea, was constructed .These results give a base for further research on enterotoxin in ETEC.

Key concepts: Enterotoxin, Enterotoxigenic Escherichia coli, Heat-stable enterotoxin, Heat-labile enterotoxin, Mutagenesis, Escherichia coli, Microbiology, Diarrhea

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