Clinical study of continuous positive airway pressure in treatment for neonatal respiratory failure

OBJECTIVE To observe the clinical effect of continuous positive airway pressure(CPAP) by nasal facemask on treatment of neonatal respiratory failure.METHODS A total of 106 cases with neonatal respiratory failure were randomly classified into two groups,53 cases in control group were treated with oxygen mask and 53 cases in treatment group were treated with CPAP.The changes of clinical effect and blood gas between the two groups were compared.RESULTS The total effective rate in observation group was 79.2%,which was significantly higher than that in control group,56.6%(P0.05).The level of pH,PaO2,PaCO2 and SaO2 was(7.35±0.18),(10.42±2.67),(6.22±1.59),and(96.85±15.58)% in observation after treatment while was(7.29±0.17),(7.11±1.52)kPa,(6.15±1.57)kPa and(83.26±12.71)% in control group.Compared with pre-treatment,the PaO2 and SaO2 was significantly increased(P0.05)after treatment but no significant differences in pH and PaCO2 in both two groups.Moreover,the levels of PaO2 and SaO2 in observation group after treatment were significantly higher than those in control group(P0.05).CONCLUSION CPAP in treatment with neonatal respiratory failure can improve the clinical effect and increase PaO2 and SaO2,which is worthy of being promoted and applied in clinic.