Nasal Continuous Positive Airway Pressure(NCPAP) and Conventional Mechanical Ventilation(CMV) for Premature with Respiratory Failure

Objective To observe the effect of nasal continuous positive airway pressure(NCPAP) and conventional mechanical ventilation(CMV) for preterm babies with respiratory failure.Methods From Jan.2002 to Dec.2009,a total of 43 preterm babies with respiratory failure who hospitalized in the neonatal department were enrolled in the study.20 of them were treated with NCPAP(NCPAP group),others were treated with CMV(CMV group).The changes of blood gas analysis were monitored before and after treatment for 24 hours.Recovery rate and oxygen time were also studied.Results The blood gas analysis results of all the babies after treatment for 24 hours showed significant differences compared with that of babies before treatment,and the differences in changes of the analysis results between the two groups were significant(P0.01).Recovery rate of NCPAP group was 45.0%,while that of CMV group was 78.3%,there was also significant difference(χ2=5.065,P0.05).But there was no significant difference of oxygen time between the two groups.Conclusion NCPAP is effective and safe for preterm babies with respiratory failure.However,the appropriate indications must be strictly observed.CMV should be applied when the disease development.