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[Expression of aquaporin-1,3 in the cochlea and endolymphatic sac of guinea pig].

Qi Li, Lin Lin, Yinyan Hu, Deliang Huang

Abstract

OBJECTIVE: To detect the expression of Aquaporin-1,3 in the cochlea and endolymphatic sac of guinea pig. METHOD: Two-step immunohistochemical method and immunofluorescence was used to examine the expression of Aquaporin-1,3. RESULT: Aquaporin-1 was expressed on the basilar part of spiral ligament, basal membrane of Corti's organ and epithelialis of scala tympani, and basilar part under the cellular epithelialis in endolymphatic sac. Aquaporin-3 was expressed on stria vascularis, spiral ligament, Corti's organ, spiral ganglion and, the basilar part and the cellular epithelialis in endolymphatic sac. CONCLUSION: Aquaporin-1,3 were widely expressed in the cochlea and endolymphatic sac of guinea pig.

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Available abstract

Key concepts: Endolymphatic sac, Basilar membrane, Spiral ganglion, Organ of Corti, Spiral ligament, Cochlea, Guinea pig, Endolymphatic hydrops