Pulmonary Function of Convalescent Patients with SARS:A five-year successive observation
Kun Peng
Abstract
Kun Peng
Abstract
Objective To investigate the remote outcome of pulmonary dysfunction left in patients with serious acute respiratory syndrome(SARS)through observing the functional changes of convalescent SARS patients.Methods Totally 46 SARS patients were divided as normal and abnormal groups according to their pulmonary diffusion function.Seven-time follow-ups were conducted in five years to observe the changing trends of pulmonary function for the patients in the two groups.Results During the follow-ups in the five years,in normal group no statistically significant changes were found(P0.05);but in abnormal group,there were significantly increasing trends in the three parameters of diffusing capacity of the lung for carbon monoxide predicted percent(DLco%),total lung capacity predicted percent(TLC%)and residual volume predicted percent(RV%)(P0.05).Conclusion The damages of pulmonary function induced by SARS were different from that in pulmonary fibrosis,most of which could recover gradually.
A significance statement is not available in the OpenAlex record.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
Objective To investigate the remote outcome of pulmonary dysfunction left in patients with serious acute respiratory syndrome(SARS)through observing the functional changes of convalescent SARS patients.Methods Totally 46 SARS patients were divided as normal and abnormal groups according to their pulmonary diffusion function.Seven-time follow-ups were conducted in five years to observe the changing trends of pulmonary function for the patients in the two groups.Results During the follow-ups in the five years,in normal group no statistically significant changes were found(P0.05);but in abnormal group,there were significantly increasing trends in the three parameters of diffusing capacity of the lung for carbon monoxide predicted percent(DLco%),total lung capacity predicted percent(TLC%)and residual volume predicted percent(RV%)(P0.05).Conclusion The damages of pulmonary function induced by SARS were different from that in pulmonary fibrosis,most of which could recover gradually.
Key concepts: Medicine, DLCO, Pulmonary function testing, Pulmonary fibrosis, Diffusing capacity, Lung volumes, Severe acute respiratory syndrome, Internal medicine