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Phylogeny of human mitochondrial DNA lineages and its applications

Kong Qing-peng, Zhang Ya-ping

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Abstract

With the special intention to introduce the most widely adopted phylogenetic analysis human mitochondrial DNA (mtDNA)studies,the history of the reconstruction of mtDNA phylogeny was reviewed.And the applications of human mtDNA phylogeny in studying human evolution,estimating the quality of mtDNA data,and distilling the disease-associated mtDNA mutation were then summarized in the present review.

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What this paper is about

With the special intention to introduce the most widely adopted phylogenetic analysis human mitochondrial DNA (mtDNA)studies,the history of the reconstruction of mtDNA phylogeny was reviewed.And the applications of human mtDNA phylogeny in studying human evolution,estimating the quality of mtDNA data,and distilling the disease-associated mtDNA mutation were then summarized in the present review.

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Available abstract

With the special intention to introduce the most widely adopted phylogenetic analysis human mitochondrial DNA (mtDNA)studies,the history of the reconstruction of mtDNA phylogeny was reviewed.And the applications of human mtDNA phylogeny in studying human evolution,estimating the quality of mtDNA data,and distilling the disease-associated mtDNA mutation were then summarized in the present review.

Key concepts: Mitochondrial DNA, Phylogenetics, Biology, Phylogenetic tree, Evolutionary biology, Human mitochondrial genetics, Genetics, Computational biology

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