2010•Huanjing yu zhiye yixueRequires access
CYP1A1*2C gene polymorphisms in Miao, Buyi populations of Chinese Guizhou Province.
Zheng Bo, Haiyan Huang, Bing Zhang, Xiaomei Wang, Jianjun Liu
Open publisher page 0 citations
Abstract
[ Objective] To investigate the gene polymorphisms of CYP1A1*2C in Chinese Miao, Buyi nationalities. [Methods] Taqman-MGB probe was used in real-time RealTime-PCR to test the polymorphisms of CYP1A1*2C in Chinese Miao(125), Buyi(122)people, and the significant difference between Miao and Buyi was checked by χ2 test.[ Results] The distribution of wild homozygote(genetic type AA), mutant heterozygote(genetic type AG), mutant homozygote(genetic type GG)of CYP1A1*2C in Chinese Miao, Buyi populations were 65.6%, 28.0%, 6.4% and 68.9%, 25.4%, 5.7%, respectively. The distribution of A and G allele frequency of CYP1A1*2C in Miao, Buyi populations were 79.6%, 20.4% and 81.6%, 18.4%, respectively.[ Conclusion] The distribution of genetic frequency and allele gene frequency of CYP1A1*2CC are without statistically significance in difference between Miao, Buyi nationalities in Guizhou Province China.