2003Journal of Tianjin Normal UniversityRequires access

Research on the Stability of Injection and Powder form of Recombinant Human Interferon α-2b

Yu Jian

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Abstract

In order to evaluate the stability of injection and powder form of interferon α2b, the cytopathogenic effect (CPE) was applied to assay the antiviral activity of them that stored for different periods of time at 4℃, and compared with those of standard interferon. The results showed that injection and powder are of the same antiviral activity even though after two years of storage, and showed better protective effect on cells than that of standard interferon. It demonstrated the stability of injection and powder form of interferon α2b are reliable.

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What this paper is about

In order to evaluate the stability of injection and powder form of interferon α2b, the cytopathogenic effect (CPE) was applied to assay the antiviral activity of them that stored for different periods of time at 4℃, and compared with those of standard interferon. The results showed that injection and powder are of the same antiviral activity even though after two years of storage, and showed better protective effect on cells than that of standard interferon. It demonstrated the stability of injection and powder form of interferon α2b are reliable.

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Available abstract

In order to evaluate the stability of injection and powder form of interferon α2b, the cytopathogenic effect (CPE) was applied to assay the antiviral activity of them that stored for different periods of time at 4℃, and compared with those of standard interferon. The results showed that injection and powder are of the same antiviral activity even though after two years of storage, and showed better protective effect on cells than that of standard interferon. It demonstrated the stability of injection and powder form of interferon α2b are reliable.

Key concepts: Interferon, Recombinant DNA, Chemistry, Virology, Biology, Biochemistry, Gene

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