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2014•Guangxi Medical JournalRequires access

Correlation of Waist-Hip Ratio with Sex Hormone Binding Globulin and Free Testosterone in Perimenopausal Women with Obesity

Yang Xiao-mi

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Abstract

Objective To investigate the correlation of waist-hip ratio( WHR) with sex hormone binding globulin( SHBG) and free testosterone in perimenopausal women with obesity. Methods Eighty obesity women aged 40 ~50 years old were divided into group Ⅰ and group Ⅱ according to WHR,with 40 cases in each group,and the serum levels of free testosterone,SHBG were detected,and body mass index( BMI) was calculated. The free androgen index( FAI) was used as the indicator of androgen activity. Results FAI and WHR in group Ⅰ were higher than those in group Ⅱ( all P 0. 05),while the level of SHBG was lower than that in group Ⅱ( P 0. 05); WHR negatively correlated with SHBG( P 0. 05),and positively correlated with FAI and BMI among perimenopausal women with obesity( P 0. 05).Conclusion WHR negatively correlates with SHBG while positively correlates with FAI and BMI among perimenopausal women with obesity.

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Objective To investigate the correlation of waist-hip ratio( WHR) with sex hormone binding globulin( SHBG) and free testosterone in perimenopausal women with obesity. Methods Eighty obesity women aged 40 ~50 years old were divided into group Ⅰ and group Ⅱ according to WHR,with 40 cases in each group,and the serum levels of free testosterone,SHBG were detected,and body mass index( BMI) was calculated. The free androgen index( FAI) was used as the indicator of androgen activity. Results FAI and WHR in group Ⅰ were higher than those in group Ⅱ( all P 0. 05),while the level of SHBG was lower than that in group Ⅱ( P 0. 05); WHR negatively correlated with SHBG( P 0. 05),and positively correlated with FAI and BMI among perimenopausal women with obesity( P 0. 05).Conclusion WHR negatively correlates with SHBG while positively correlates with FAI and BMI among perimenopausal women with obesity.

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Available abstract

Objective To investigate the correlation of waist-hip ratio( WHR) with sex hormone binding globulin( SHBG) and free testosterone in perimenopausal women with obesity. Methods Eighty obesity women aged 40 ~50 years old were divided into group Ⅰ and group Ⅱ according to WHR,with 40 cases in each group,and the serum levels of free testosterone,SHBG were detected,and body mass index( BMI) was calculated. The free androgen index( FAI) was used as the indicator of androgen activity. Results FAI and WHR in group Ⅰ were higher than those in group Ⅱ( all P 0. 05),while the level of SHBG was lower than that in group Ⅱ( P 0. 05); WHR negatively correlated with SHBG( P 0. 05),and positively correlated with FAI and BMI among perimenopausal women with obesity( P 0. 05).Conclusion WHR negatively correlates with SHBG while positively correlates with FAI and BMI among perimenopausal women with obesity.

Key concepts: Sex hormone-binding globulin, Free androgen index, Body mass index, Internal medicine, Obesity, Testosterone (patch), Free testosterone, Endocrinology

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Correlation of Waist-Hip Ratio with Sex Hormone Binding Globulin and Free Testosterone in Perimenopausal Women with Obesity — Research Paper | ScholarLens