New opinion on the mechanisms of general anesthesia:post-translational modification of proteins

Studying the post-translational modification of intracellular functional proteins is the newest progresses in the fleld of general anesthesia mechanisms research. In this review, the authors indicate that three rapid intracellular protein modifications as phosphorylation, ubiquitination, and sumoylation, are participated in the mechanisms of general anesthesia, and show their experimental results about the effects of ubiquitination and sumoylation modifications on the mechanisms of general anesthetics.