Clinical Research on the Electro-acupuncture Combined with DangfeiLiganning Capsule in the Treatment of Nonalcoholic Fatty Liver Disease

Objective: To investigate the efficacy and safety of electro-acupuncture combined with Dangfei Liganning Capsule in the treatment of Nonalcoholic Fatty Liver Disease(NASH). Methods: Eighty patients who were diagnosed as NASH according to 2010 nonalcoholic fatty liver disease diagnosis and treatment guideline were randomly divided into the combination group(electro-acupuncture combined with Dangfei Liganning Capsule) and control group(Hugan Ning). The patients in both groups were treated by correcting unhealthy lifestyles, dietary control(BMI24), moderate aerobic exercise on the basis of the corresponding treatment. The control group was given Hugan Ning, 3 times/d, while the combination group was given Dangfei Liganning Capsule with electro-acupuncture acupoints. The changes of ALT, GGT levels, the severity of fatty liver and the adverse reaction were observed and compared. Results: The total effective rate of combination group and control group were respectively 90.0% and 62.5%(P0.05). The aminotransferase and blood fat of combination group were decreased significantly than those of the control group(P0.05). No significant adverse reaction was found. Conclusion: Electro-acupuncture combined with Dangfei Liganning Capsule may obtain a favorable effect on nonalcoholic fatty liver disease and was of great clinical value.