2006Chemistry worldRequires access

Synthesis and Herbicidal Activity of 3-Chloro-4-fluorobenzoylthiourea

Changchun Liu

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Abstract

3-Chloro-4-fluorobenzoylthiourea was synthesized by the reaction of 2-amino-4,6-dimethoxy pyrimidine with 3-chloro-4-fluorobenzoyl isosulfocyanic ester,which was prepared from 3-chloro-4-fluorobenzoic acid by chloration and acylation.Its structure was characterized by IR,()~1H NMR and elemental analysis.The preliminary biologic tests show the compound have good herbicidal activity.

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What this paper is about

3-Chloro-4-fluorobenzoylthiourea was synthesized by the reaction of 2-amino-4,6-dimethoxy pyrimidine with 3-chloro-4-fluorobenzoyl isosulfocyanic ester,which was prepared from 3-chloro-4-fluorobenzoic acid by chloration and acylation.Its structure was characterized by IR,()~1H NMR and elemental analysis.The preliminary biologic tests show the compound have good herbicidal activity.

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Available abstract

3-Chloro-4-fluorobenzoylthiourea was synthesized by the reaction of 2-amino-4,6-dimethoxy pyrimidine with 3-chloro-4-fluorobenzoyl isosulfocyanic ester,which was prepared from 3-chloro-4-fluorobenzoic acid by chloration and acylation.Its structure was characterized by IR,()~1H NMR and elemental analysis.The preliminary biologic tests show the compound have good herbicidal activity.

Key concepts: Chemistry, Acylation, Elemental analysis, Proton NMR, Pyrimidine, Organic chemistry, Stereochemistry, Combinatorial chemistry

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