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2013•International Journal of Pathology and Clinical MedicineRequires access

Advances in the study of NGAL in early diagnosis and treatment for acute kidney injury

Ze-Min Kuang

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Abstract

There are few sensitivity and specific biomarkers in early diagnosis for acute kidney injury(AKI).Nowadays more attentions are paid on a new biomarker named neutrophil gelatinase-associated lipocalin(NGAL).Many studies have shown that NGAL is a powerful predictor on AKI.Meanwhile some observations have found that recombinant NGAL plays a role in protection of renal tubule.This review will present the function of NGAL in early diagnosis and treatment for AKI.

About this research paper

What this paper is about

There are few sensitivity and specific biomarkers in early diagnosis for acute kidney injury(AKI).Nowadays more attentions are paid on a new biomarker named neutrophil gelatinase-associated lipocalin(NGAL).Many studies have shown that NGAL is a powerful predictor on AKI.Meanwhile some observations have found that recombinant NGAL plays a role in protection of renal tubule.This review will present the function of NGAL in early diagnosis and treatment for AKI.

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Available abstract

There are few sensitivity and specific biomarkers in early diagnosis for acute kidney injury(AKI).Nowadays more attentions are paid on a new biomarker named neutrophil gelatinase-associated lipocalin(NGAL).Many studies have shown that NGAL is a powerful predictor on AKI.Meanwhile some observations have found that recombinant NGAL plays a role in protection of renal tubule.This review will present the function of NGAL in early diagnosis and treatment for AKI.

Key concepts: Acute kidney injury, Lipocalin, Medicine, Biomarker, Neutrophil gelatinase-associated lipocalin, Renal function, Intensive care medicine, Kidney

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