Clinical effects of sodium hyaluronate gel in prevention of postoperative adhesion after gynecological and obstetric abdominal and pelvic surgery

Objective To observe the clinical effects of sodium hyaluronate gel in the prevention of postoperative adhesion after gynecological and obstetric abdominal and pelvic surgery. Methods Eighty patients receiving gynecological and obstetric abdominal and pelvic surgery in our hospital were divided into the observation group and the control group equally, with 40 patients in each group. The control group received conventional surgery treatment and the observation group received additional sodium hyaluronate gel on the basis of the control group. The postoperative initial adhesion rate and severe adhesion rate, the interleukin-6, interleukin-10 and tumor necrosis factor-a concentrations, and the hemorheological parameters were examined. Results The observation group was significantly lower than the control group in the postoperative initial adhesion rate and severe adhesion rate ( P 0.05), significantly higher in the IL-6, IL-10 and TNF-α concentrations (P 0.05), and significantly lower in the hemorheological parameters (P 0.05). Conclusion In the prevention of postoperative adhesion after gynecological and obstetric abdominal and pelvic surgery, the sodium hyaluronate gel has obvious efficacy and can reduce the postoperative adhesion rate of patients, thereby worthy of clinical promotion and application.