Analysis of Epidemic Characteristics and Prevention and Control Measures of HFRS in Zixing City from 1971 to 2012

Objective To analyze the monitoring data of hemorrhagic fever with renal syndrome(HFRS) and provide a basis for the formulation of the HFRS prevention and control measures.Methods The monitoring data of the epidemic characteristics,host animals and incidence in general population of HFRS in Zixing from 1971 to 2012 were collected and analyzed.Results Totally,1,045 cases and 62 mortalities of HFRS were reported during the past 42 years.The average annual incidence and related mortality were 7.42/100,000 and 5.93%,respectively.The patients aged 20 to 60 years accounted for 81.34%,and 80.11% of the cases were farmers.HFRS occurred all through the year,mainly in winter and spring.The rat density ranged from 6.76% to 9.5%.The virus carried rate was 3.67%-7.63% in Apodemusagrarius and 1.83%-5.29% in Rattus norvegicus.The recessive infection rate of HFRS in the general population was 2.67%-24.65%.The seroconversion rate after vaccination was 81%.Conclusions Zixing is the natural focus for the wild-rat types and house-rat types of HFRS.The Apodemus agrarius and Rattus horvegicus are the main host animals and infection sources.Strengthening HFRS monitoring,developing vaccination in the key populations,and deratization and controlling rodents are main effective measures for the prevention and control of HFRS.