Surveillance of antimicrobial resistance among Escherichia coli isolates from different animals in Sichuan Province in 2007

The MICs of 13 kinds of antimicrobial agents to E.coli isolates from healthy cattle,swine and poultry in Sichuan Province in 2007 were determined by broth micro-dilution method.The results showed that these isolates were high resistance to most of antimicrobial agents(except the resistance to amikacin was 5.85%,other antimicrobial resistance rates were more than 35%).The frequency of resistance to sulfasoxazole,sulfamethoxazole+trimethoprim(19∶1) and ampicillin was 100%,96.6% and 75.8% respectively.Multi-drug resistance was serious: 92.6% of strains were resistant to at least 3 kinds of antimicrobial agents.Resistance degrees were variable among regions and animals.The resistance rates in Chengdu are higher than those in other cities,and the highest resistance strains of E.coli were isolated from poultry.The result suggests that the antimicrobial resistance of E.coli is severe,and it's necessary to strengthen the surveillance of antimicrobial resistance and give some directions to clinical medication.