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[Studies on alkalodial constituents in leaves of Uncaria hirsuta].

Wen-bo Xin, Ping Dao Gu, Gui‐Xin Chou, Zhengtao Wang

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Abstract

OBJECTIVE: To study the alkaloidial constituents of the leaves of uncaria hirsuta. METHOD: Some chromatographic methods were applied to isolate pure compounds and their structures were elucidated by spectroscopic methods. RESULT: Eleven compounds were isolated and identified as 19-epi-3-iso-ajmalicine (1), 3-isoajmalicine (2), harman (3), mitraphylline (4), isomitraphylline (5), isorhynchophylline (6), corynoxine (7), rhynchophylline (8), isomitraphyllic acid (9), uncarine A (10) and uncarine B (11). CONCLUSION: Compounds 1-9 were firstly isolated from this plant.

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What this paper is about

OBJECTIVE: To study the alkaloidial constituents of the leaves of uncaria hirsuta. METHOD: Some chromatographic methods were applied to isolate pure compounds and their structures were elucidated by spectroscopic methods. RESULT: Eleven compounds were isolated and identified as 19-epi-3-iso-ajmalicine (1), 3-isoajmalicine (2), harman (3), mitraphylline (4), isomitraphylline (5), isorhynchophylline (6), corynoxine (7), rhynchophylline (8), isomitraphyllic acid (9), uncarine A (10) and uncarine B (11). CONCLUSION: Compounds 1-9 were firstly isolated from this plant.

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Available abstract

OBJECTIVE: To study the alkaloidial constituents of the leaves of uncaria hirsuta. METHOD: Some chromatographic methods were applied to isolate pure compounds and their structures were elucidated by spectroscopic methods. RESULT: Eleven compounds were isolated and identified as 19-epi-3-iso-ajmalicine (1), 3-isoajmalicine (2), harman (3), mitraphylline (4), isomitraphylline (5), isorhynchophylline (6), corynoxine (7), rhynchophylline (8), isomitraphyllic acid (9), uncarine A (10) and uncarine B (11). CONCLUSION: Compounds 1-9 were firstly isolated from this plant.

Key concepts: Chemical constituents, Chemistry, Traditional medicine, Chromatography, Medicine

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