Effect of 0.12% Chlorhexidine with Negative Pressure Suction Toothbrush in Orotracheal Intubation Patients

Objective To explore the effect of 0.12% chlorhexidine with negative pressure suction toothbrush in patients with mechanical ventilation through orotracheal intubation. Methods Seventy patients undergoing mechanical ventilation through orotracheal intubation from October 2012 to November 2013 were randomly divided into observation group(n=35, but 2 patients were removed) and control group(n=35). With 0.12% chlorhexidine as standard oral care solution, negative pressure toothbrush was applied in observation group for oral care while in control group traditional mouth scrubbing was used for 4 times/d for seven days. Oropharyngeal bacterial culture detection rate before and after oral care was compared and the incidence of oral odor two hours after oral care and ventilator-associated pneumonia(VAP) were recorded. Results The oropharyngeal bacterial culture detection rate and incidence of oral odor and VAP in observation group were lower than those in control group(P0.05). Conclusion 0.12% chlorhexidine with negative pressure suction toothbrush is beneficial to eliminating bad breath, reducing oropharyngeal bacterial propagation and the incidence of VAP for patients with mechanical ventilation through orotracheal intubation.