Pathological invasiveness of lung adnenocarcinomas presenting as ground-glass opacity with different proportion of consolidation

Objective To compare the difference of pathological invasiveness between lung adnenocarcinomas presenting as ground-glass opacity(GGO) with different proportion of consolidation.Methods CT and pathological data of 59 patients with adenocarcinoma confirmed by pathology presenting as GGO on CT were retrospectively studied.The thin-slice images of the focal lesions were analyzed and according to the maximal diameter ratio of the consolidation and the tumor,the patients were divided into main GGO group(G_G) and main consolidation group(G_C).The CT features and pathological invasiveness of the tumor were observed and compared.Results The diameter of the lesions was(2.71±1.08)cm.There were 8 of pure GGOs and 51 of mixed GGOs.Bubble-like low attenuation appeared in 43(43/59,72.88%) cases and most of the lesions(53/59,89.83%) had clear margin.There were 19 cases in G_G group and 40 cases in G_C group.CT features:There was not obvious difference of the tumor diameter,location,shape and clear margin between the two groups(all P0.05).The ratios of lobulated and(or) burr margin,sign of bubble-like attenuation and pleural indentation in G_C group were higher than those in G_G group(all P0.05).Pathology results:No differences of lymph node metastasis and cancer embolus were found(both P0.05) between the two groups.The rate of pleural invasion and the pathological staging were higher in G_C group than those in G_G group(both P0.05).Conclusion With increasing of the solid component ratio in lung adenocarcinas presenting as GGO,the lesions are tended to demonstrate malignant features in CT and high invasiveness in pathology.