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2008•The Journal of Medical Theory and PracticeRequires access

The Detection of the AmpC and Extended-Spectrum β-Lactamases and the Analysis of Resistance of the Microorganism

Jin Zhang

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Abstract

Objective:To investigate ESBLs,AmpC-producing microorganism positive rute and drug resistance in order to be taken as a guide in clinical application.Methods:Bacteria was indentified by API series reagents,ESBLs and AmpC were detected by improved three dimensional test.Results:There were 117 isolates of ESBLs and AmpC-producing Gram-negative bacilli in 400 strains,positive rates of AmpC and ESBLs was 3.8% and 25.5% respectively.The resistant rate of the ESBLs and AmpC to 16 kinds of antibiotics was higher than the average.Conclusions:Resistance rate of AmpC,ESBLs-producing microorganism to most antibiotics is more than 50%.Carbopenems can be chosen as clinical experiential medication.

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What this paper is about

Objective:To investigate ESBLs,AmpC-producing microorganism positive rute and drug resistance in order to be taken as a guide in clinical application.Methods:Bacteria was indentified by API series reagents,ESBLs and AmpC were detected by improved three dimensional test.Results:There were 117 isolates of ESBLs and AmpC-producing Gram-negative bacilli in 400 strains,positive rates of AmpC and ESBLs was 3.8% and 25.5% respectively.The resistant rate of the ESBLs and AmpC to 16 kinds of antibiotics was higher than the average.Conclusions:Resistance rate of AmpC,ESBLs-producing microorganism to most antibiotics is more than 50%.Carbopenems can be chosen as clinical experiential medication.

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Available abstract

Objective:To investigate ESBLs,AmpC-producing microorganism positive rute and drug resistance in order to be taken as a guide in clinical application.Methods:Bacteria was indentified by API series reagents,ESBLs and AmpC were detected by improved three dimensional test.Results:There were 117 isolates of ESBLs and AmpC-producing Gram-negative bacilli in 400 strains,positive rates of AmpC and ESBLs was 3.8% and 25.5% respectively.The resistant rate of the ESBLs and AmpC to 16 kinds of antibiotics was higher than the average.Conclusions:Resistance rate of AmpC,ESBLs-producing microorganism to most antibiotics is more than 50%.Carbopenems can be chosen as clinical experiential medication.

Key concepts: Microbiology, Medicine, Bacilli, Microorganism, Antibiotics, Drug resistance, Bacteria, Antibiotic resistance

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