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2008•Chinese Journal of Geriatric CareRequires access

The Clinical Significance of T Lymphocyte Subsets in Peripheral Blood of Elderly Patients with Esophageal Carcinoma

Xi Chen

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Abstract

Objective To investigate the clinic value of the variation of T lymphocyte subsets in peripheral blood of el- derly esophagus cancer patients. Methods Flow cytometry was used to test some immune indexes,including CD3+,CD4+, CD8+,NK,CD4+/ CD8+ in sixty esophagus cancer patients. Results The level of CD8+ and CD4+/ CD8+ in elderly patients(60y) was significantly different from that of younger patients(≤60y,P0.05). Conclusion Detecting lymphocyte antigens by flow cytometry provides an effective basis for evaluating the immune condition of tumor patients. There were significant differ-ences of lymphocyte subsets in different age groups with esophageal carcinoma.

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What this paper is about

Objective To investigate the clinic value of the variation of T lymphocyte subsets in peripheral blood of el- derly esophagus cancer patients. Methods Flow cytometry was used to test some immune indexes,including CD3+,CD4+, CD8+,NK,CD4+/ CD8+ in sixty esophagus cancer patients. Results The level of CD8+ and CD4+/ CD8+ in elderly patients(60y) was significantly different from that of younger patients(≤60y,P0.05). Conclusion Detecting lymphocyte antigens by flow cytometry provides an effective basis for evaluating the immune condition of tumor patients. There were significant differ-ences of lymphocyte subsets in different age groups with esophageal carcinoma.

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Available abstract

Objective To investigate the clinic value of the variation of T lymphocyte subsets in peripheral blood of el- derly esophagus cancer patients. Methods Flow cytometry was used to test some immune indexes,including CD3+,CD4+, CD8+,NK,CD4+/ CD8+ in sixty esophagus cancer patients. Results The level of CD8+ and CD4+/ CD8+ in elderly patients(60y) was significantly different from that of younger patients(≤60y,P0.05). Conclusion Detecting lymphocyte antigens by flow cytometry provides an effective basis for evaluating the immune condition of tumor patients. There were significant differ-ences of lymphocyte subsets in different age groups with esophageal carcinoma.

Key concepts: Medicine, CD8, Esophagus, Flow cytometry, Immune system, Lymphocyte, Carcinoma, Esophageal cancer

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