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2010•Guiyang yixueyuan xuebaoRequires access

Effect of Qianlongtong Capsule on Expression of Caspase-3 in Prostatic Stromal Cells

Ju‐Qiao He

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Abstract

Objective: To investigate the effect of Qianlongtong capsule on expression of caspase-3 in prostatic stromal cells of patients with benign prostatic hyperplasia(BPH).Methods: Prostate stromal cells of patients with BPH were cultured in vitro.Expression level of caspase-3 in prostate stromal cells treated by Qianlongtong capsule were detected with immunohistochemistry method.Results: Different dosages of Qianlongtong capsules increased the expression of caspase-3 in a dose-dependent manner,and the differences among groups were significant(P0.01).Conclusion: Qianlongtong capsule can promote the expression of caspase-3 in prostate stromal cells of patients with BPH,which may be one of the mechanisms of Qianlongtong capsule to treat BPH.

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What this paper is about

Objective: To investigate the effect of Qianlongtong capsule on expression of caspase-3 in prostatic stromal cells of patients with benign prostatic hyperplasia(BPH).Methods: Prostate stromal cells of patients with BPH were cultured in vitro.Expression level of caspase-3 in prostate stromal cells treated by Qianlongtong capsule were detected with immunohistochemistry method.Results: Different dosages of Qianlongtong capsules increased the expression of caspase-3 in a dose-dependent manner,and the differences among groups were significant(P0.01).Conclusion: Qianlongtong capsule can promote the expression of caspase-3 in prostate stromal cells of patients with BPH,which may be one of the mechanisms of Qianlongtong capsule to treat BPH.

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Available abstract

Objective: To investigate the effect of Qianlongtong capsule on expression of caspase-3 in prostatic stromal cells of patients with benign prostatic hyperplasia(BPH).Methods: Prostate stromal cells of patients with BPH were cultured in vitro.Expression level of caspase-3 in prostate stromal cells treated by Qianlongtong capsule were detected with immunohistochemistry method.Results: Different dosages of Qianlongtong capsules increased the expression of caspase-3 in a dose-dependent manner,and the differences among groups were significant(P0.01).Conclusion: Qianlongtong capsule can promote the expression of caspase-3 in prostate stromal cells of patients with BPH,which may be one of the mechanisms of Qianlongtong capsule to treat BPH.

Key concepts: Stromal cell, Prostate, Capsule, Hyperplasia, Immunohistochemistry, Caspase 3, Medicine, Apoptosis

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