Clinical significance of the combination detection of Procalcitonin and C-reactive protein in the liver cirrhosis patients complicated with spontaneous bacterial peritonitis

Objective To explore the sensitivity and specificity of combination detection of Procalcitonin(PCT) and C-reactive protein(CRP) in the liver cirrhosis patients complicated with spontaneous bacteria1 peritonitis(SBP),and provide the evidence for clinical diagnosis.Methods The levels of PCT and CRP were detected in 45 liver cirrhosis patients complicated with SBP,45 liver cirrhosis patients without SBP and 45 general hepititis patients.Results Compared with general hepatitis patients,the levels of PCT and CRP in liver cirrhosis patients complicated with SBP were markedly higher(t=5.20,P0.05;t=7.94,P0.05);while,there were no significantly differences between liver cirrhosis group without SBP and general hepatitis group(t=1.17,P0.05;t=1.92,P0.05).The sensitivity and specificity of PCT were better than CRP.Conclusion It is more accurate to detect PCT and CRP together in early diagnosis of liver cirrhosis complicated with SBP.