Influence of Various Operative Methods on Portal Pressure of Prehepatic Portal Hypertension: An Experimental Study

Objective To explore the evidence of operative method selection of prehepatic portal hypertension (PPH). Methods Eighteen canine models of PPH was made using narrowing the portal vein. The models were divided into four groups namely, splenectomy, mesenterio caval shunt(MCS), splenectomy with periesophagocardiac vessel disconnection(PVD) and combined operation. The portal pressure was measured pre and postoperatively. Results The effect on portal decompression was excellent in MCS( P 0.001 ), good in combined operation( P 0.01 ), fair in splenectomy( P 0.05 ). There was no obvious difference between MCS and combined operation( P 0.05 ) in portal decompression. Conclusions The operation should be selected according to the state and degree of preoperative portal pressure of the patients, and the effect on portal decompression in various method. Three criteria for procedures selection are suggested.