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2003•Chinese Journal of Natural MedicinesRequires access

Chemical Constituents of Chaenomeles sinensis (Thouin) Koehne

Hui Gao

Open publisher page 11 citations

Abstract

AIM: To continue to study the anticancer constituents of EtOAc soluble fraction of the MeOH extract from the twigs of Chaenomeles sinensis (Thouin) Koehne METHOD: Compounds were isolated by silica gel columns,preparative TLC and HPLC,and their structure were identified by the physical and chemical characters especially by the spectral analysis RESULT: Seven compounds were isolated and the structure of them were identified as lup-20(29)-en-3β,24,28-triol (1),2α-hydroxyursolic acid (2),euscaphic acid(3),tormentic acid(4),lyoniresinol-9′- O -β- D -glucopyranoside(5),avicularin (6),and (-)epicatechin(7)respectively CONCLUSION: Compounds 1～6 were isolated from the Chaenomeles genus for the first time

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What this paper is about

AIM: To continue to study the anticancer constituents of EtOAc soluble fraction of the MeOH extract from the twigs of Chaenomeles sinensis (Thouin) Koehne METHOD: Compounds were isolated by silica gel columns,preparative TLC and HPLC,and their structure were identified by the physical and chemical characters especially by the spectral analysis RESULT: Seven compounds were isolated and the structure of them were identified as lup-20(29)-en-3β,24,28-triol (1),2α-hydroxyursolic acid (2),euscaphic acid(3),tormentic acid(4),lyoniresinol-9′- O -β- D -glucopyranoside(5),avicularin (6),and (-)epicatechin(7)respectively CONCLUSION: Compounds 1～6 were isolated from the Chaenomeles genus for the first time

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Available abstract

AIM: To continue to study the anticancer constituents of EtOAc soluble fraction of the MeOH extract from the twigs of Chaenomeles sinensis (Thouin) Koehne METHOD: Compounds were isolated by silica gel columns,preparative TLC and HPLC,and their structure were identified by the physical and chemical characters especially by the spectral analysis RESULT: Seven compounds were isolated and the structure of them were identified as lup-20(29)-en-3β,24,28-triol (1),2α-hydroxyursolic acid (2),euscaphic acid(3),tormentic acid(4),lyoniresinol-9′- O -β- D -glucopyranoside(5),avicularin (6),and (-)epicatechin(7)respectively CONCLUSION: Compounds 1～6 were isolated from the Chaenomeles genus for the first time

Key concepts: Chemical constituents, Chemistry, Spectral analysis, Silica gel, Chromatography, Physics, Quantum mechanics, Spectroscopy

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