Clinical Study on surgical treatment for gastric cancer patients

Objective To investigate appropriative way to improve curative effect and survival rate of surgical therapy for gastric cancer.Methods Select 407 patients with gastric carcinoma who were operated upon in the department of abdominal surgery in our hospital from October 2001 to April 2005.The survival rates were analysed with Kaplan-meier and then analysed with univarite and multivariate analysis of cox regression.Results ①In 407 cases,249 died.The median survival time of them was 29 months.over-all survival rate was 71.87%,The 3-year over-all survival rate was 45.33%,The 5-year over-all survival rate was 40.05%.13.27% of them have recurred within half a year,25.21% within one year,46.02% within three years and 51.54% within five years.②Multivariate analysis showed that four major significant factors and affect the prognosis were Borrmann types,radical gastrectomy,time of chemotherapy and TNM staging.Conclusion The reasonable plan of gastrectomy should be drawn up the survival rate of gastric cancer and the synthetic treatment around gastrectomy should be performed basing on biological characteristic of each patient such as TNM clinical stage,Brrrmann type and so on.