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2010•Journal of Tongji UniversityRequires access

A retrospective analysis of 555 cases of drug adverse reactions

Deqiu Zhu

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Abstract

Objective To analyze the characteristics and related factors of adverse drug reaction (ADR) and establish the way of clinical ADR monitoring in future.Methods A total of 555 ADR reports collected in 2008 were analyzed restrospectively.Results Among the 555 cases of ADR,the patients at the age of 20 to 59 had the highest incidence.There were 182 kinds of drugs that induced ADR,in which 70.43%(462 cases) were induced by anti-infective drugs,followed by traditional Chinese drugs preparations.Intravenous injection was the common medication inducing ADR (82.17%,539 cases.ADR were mainly manifested in skin and local lesions,than in alimentary system lesions.Conclusion Clinical departments should pay great attention in monitoring and reporting of ADR in order to reduce and avoid the occurrence of ADR and promote the rational use of drugs.

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Objective To analyze the characteristics and related factors of adverse drug reaction (ADR) and establish the way of clinical ADR monitoring in future.Methods A total of 555 ADR reports collected in 2008 were analyzed restrospectively.Results Among the 555 cases of ADR,the patients at the age of 20 to 59 had the highest incidence.There were 182 kinds of drugs that induced ADR,in which 70.43%(462 cases) were induced by anti-infective drugs,followed by traditional Chinese drugs preparations.Intravenous injection was the common medication inducing ADR (82.17%,539 cases.ADR were mainly manifested in skin and local lesions,than in alimentary system lesions.Conclusion Clinical departments should pay great attention in monitoring and reporting of ADR in order to reduce and avoid the occurrence of ADR and promote the rational use of drugs.

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Available abstract

Objective To analyze the characteristics and related factors of adverse drug reaction (ADR) and establish the way of clinical ADR monitoring in future.Methods A total of 555 ADR reports collected in 2008 were analyzed restrospectively.Results Among the 555 cases of ADR,the patients at the age of 20 to 59 had the highest incidence.There were 182 kinds of drugs that induced ADR,in which 70.43%(462 cases) were induced by anti-infective drugs,followed by traditional Chinese drugs preparations.Intravenous injection was the common medication inducing ADR (82.17%,539 cases.ADR were mainly manifested in skin and local lesions,than in alimentary system lesions.Conclusion Clinical departments should pay great attention in monitoring and reporting of ADR in order to reduce and avoid the occurrence of ADR and promote the rational use of drugs.

Key concepts: Medicine, Incidence (geometry), Drug, Adverse drug reaction, Drug reaction, Pharmacology, Adverse effect, Internal medicine

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