2007•Lishizhen Medicine and Materia Medica ResearchRequires access

Experimental Study on Acute Toxicity of Compound Ginkgo biloba Tablets in Mice

Mei Lü

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Abstract

Objective To study the toxic reaction on Compound Ginkgo biloba Tablets in mice.Methods The maximum administration dosage of Compound Ginkgo biloba Tablets were determined by ig administration in mice,three times a day.Its acute toxic reactions were observed for 7 days.Results All mice were survive,and no toxic reaction was shown during the observed period .The average rate of its increasing weight was 24.82 percent.The maximum administration dosage was 3 339.6 mg of puerarin given to mice per kilogram,equivalent to men's daily administration dosage by 2360.1 times.Conclusion Compound Ginkgo biloba Tablets is safe for oral administration.

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What this paper is about

Objective To study the toxic reaction on Compound Ginkgo biloba Tablets in mice.Methods The maximum administration dosage of Compound Ginkgo biloba Tablets were determined by ig administration in mice,three times a day.Its acute toxic reactions were observed for 7 days.Results All mice were survive,and no toxic reaction was shown during the observed period .The average rate of its increasing weight was 24.82 percent.The maximum administration dosage was 3 339.6 mg of puerarin given to mice per kilogram,equivalent to men's daily administration dosage by 2360.1 times.Conclusion Compound Ginkgo biloba Tablets is safe for oral administration.

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Available abstract

Objective To study the toxic reaction on Compound Ginkgo biloba Tablets in mice.Methods The maximum administration dosage of Compound Ginkgo biloba Tablets were determined by ig administration in mice,three times a day.Its acute toxic reactions were observed for 7 days.Results All mice were survive,and no toxic reaction was shown during the observed period .The average rate of its increasing weight was 24.82 percent.The maximum administration dosage was 3 339.6 mg of puerarin given to mice per kilogram,equivalent to men's daily administration dosage by 2360.1 times.Conclusion Compound Ginkgo biloba Tablets is safe for oral administration.

Key concepts: Ginkgo biloba, Pharmacology, Ginkgoales, Oral administration, Ginkgo, Acute toxicity, Traditional medicine, Medicine

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