2008•Medical Journal of the Chinese People's Armed Police ForcesRequires access

Relationship between bile reflux and severity of gastric mucosa injury

WU Ben-yan

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Abstract

Objective To study the relationship between bile reflux and gastric mucosa injury.Methods The changes of intragastric bile reflux during 24 h were assessed by using ambulatory bilirubin monitoring technique in 44 subjects,including 11 without mucosa injury,16 with slight injury,and 17 with peptic ulcer.Results The number of subjects whose reflux-area was ≥20 in peptic ulcer group was significantly greater than those in other groups(P0.05).The number of subjects whose frequency of long reflux was ≥10 times in peptic ulcer group and slightly injured group was significantly greater than that in not injured group(P0.05).Conclusions There is a relationship between bile reflux and severity of gastric mucosa injury.The areas of reflux and the frequency of long reflux play a important role in causing severity of gastric mucosa injury.

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Objective To study the relationship between bile reflux and gastric mucosa injury.Methods The changes of intragastric bile reflux during 24 h were assessed by using ambulatory bilirubin monitoring technique in 44 subjects,including 11 without mucosa injury,16 with slight injury,and 17 with peptic ulcer.Results The number of subjects whose reflux-area was ≥20 in peptic ulcer group was significantly greater than those in other groups(P0.05).The number of subjects whose frequency of long reflux was ≥10 times in peptic ulcer group and slightly injured group was significantly greater than that in not injured group(P0.05).Conclusions There is a relationship between bile reflux and severity of gastric mucosa injury.The areas of reflux and the frequency of long reflux play a important role in causing severity of gastric mucosa injury.

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Available abstract

Objective To study the relationship between bile reflux and gastric mucosa injury.Methods The changes of intragastric bile reflux during 24 h were assessed by using ambulatory bilirubin monitoring technique in 44 subjects,including 11 without mucosa injury,16 with slight injury,and 17 with peptic ulcer.Results The number of subjects whose reflux-area was ≥20 in peptic ulcer group was significantly greater than those in other groups(P0.05).The number of subjects whose frequency of long reflux was ≥10 times in peptic ulcer group and slightly injured group was significantly greater than that in not injured group(P0.05).Conclusions There is a relationship between bile reflux and severity of gastric mucosa injury.The areas of reflux and the frequency of long reflux play a important role in causing severity of gastric mucosa injury.

Key concepts: Reflux, Gastroenterology, Bile reflux, Internal medicine, Medicine, Gastric mucosa, Ambulatory, Peptic ulcer

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