Relationship between bile reflux and severity of gastric mucosa injury
WU Ben-yan
Abstract
WU Ben-yan
Abstract
Objective To study the relationship between bile reflux and gastric mucosa injury.Methods The changes of intragastric bile reflux during 24 h were assessed by using ambulatory bilirubin monitoring technique in 44 subjects,including 11 without mucosa injury,16 with slight injury,and 17 with peptic ulcer.Results The number of subjects whose reflux-area was ≥20 in peptic ulcer group was significantly greater than those in other groups(P0.05).The number of subjects whose frequency of long reflux was ≥10 times in peptic ulcer group and slightly injured group was significantly greater than that in not injured group(P0.05).Conclusions There is a relationship between bile reflux and severity of gastric mucosa injury.The areas of reflux and the frequency of long reflux play a important role in causing severity of gastric mucosa injury.
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Objective To study the relationship between bile reflux and gastric mucosa injury.Methods The changes of intragastric bile reflux during 24 h were assessed by using ambulatory bilirubin monitoring technique in 44 subjects,including 11 without mucosa injury,16 with slight injury,and 17 with peptic ulcer.Results The number of subjects whose reflux-area was ≥20 in peptic ulcer group was significantly greater than those in other groups(P0.05).The number of subjects whose frequency of long reflux was ≥10 times in peptic ulcer group and slightly injured group was significantly greater than that in not injured group(P0.05).Conclusions There is a relationship between bile reflux and severity of gastric mucosa injury.The areas of reflux and the frequency of long reflux play a important role in causing severity of gastric mucosa injury.
Key concepts: Reflux, Gastroenterology, Bile reflux, Internal medicine, Medicine, Gastric mucosa, Ambulatory, Peptic ulcer