Diagnostic value of micro-calcification as the only character in breast cancer by mammography

Objective: To discuss the significance of cluster micro-calcification in the diagnosis of breast cancer by mammography. Methods: Thirty-four patients were stained by computer-aid stereotactic mammography and then resected; the resected specimen was sent to pathological department which was marked by a wire under mammography post-operation together with the photo, then compared with the characteristics of micro-calcification between benign lesions and malignant lesions, such as area, number in unit area, shape, size, spatial arrangement and short-time change and so on. Results: In all 34 cases, 18 were breast cancer. 6 cases of these 18 patients were ductal carcinoma in situ (DCIS), 4 cases were early invasive carcinoma; 8 cases were located invasion, the other 16 cases were benign. In addition, the number of calcification were more than 20 in 83.33% of malignant lesions, and less than or equal to 20 in the 68.75% of benign lesions in unit area. While the multiform calcification were showed in 66.67% of malignant lesions, sand-like calcification were showed in 68.75% of benign lesions, 44.44% of malignancy of micro-calcification were along with duct, but no duct along with calcification in benign lesions. In short-time follow-up, increased with the micro-calcification was the appearance of malignancy, and decreased with the micro-calcification was confirmed as the benign lesions. Conclusion: Characteristics of breast cancer as follows: distribution of multiform and cluster of micro-calcification were along with duct, the number of calcification were more than 20 in unit area, and sharply increasing in short-time follow-up.