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2009•Progress in Veterinary MedicineRequires access

Progress on an Endogenous Gaseous Signal Molecule Hydrogen Sulfide

Xiao Peng

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Abstract

Hydrogen sulfide is an endogenous gaseous signal molecule which is found after NO and CO.It is induced by cystathionine-β-synthase(CBS) and cystathionine-γ-lyase(CSE) catalysis in the body,It is distributed widely in the body.In the body,it participates in expanding blood vessels,inhibiting smooth muscle cell proliferation and so on.And it plays an important role in pulmonary hypertension,endotoxin shock,surgical trauma and various pathological processes of disease.The generation,metabolism,physiological role and relationship with disease of H2S were reviewed in the article.

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What this paper is about

Hydrogen sulfide is an endogenous gaseous signal molecule which is found after NO and CO.It is induced by cystathionine-β-synthase(CBS) and cystathionine-γ-lyase(CSE) catalysis in the body,It is distributed widely in the body.In the body,it participates in expanding blood vessels,inhibiting smooth muscle cell proliferation and so on.And it plays an important role in pulmonary hypertension,endotoxin shock,surgical trauma and various pathological processes of disease.The generation,metabolism,physiological role and relationship with disease of H2S were reviewed in the article.

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Available abstract

Hydrogen sulfide is an endogenous gaseous signal molecule which is found after NO and CO.It is induced by cystathionine-β-synthase(CBS) and cystathionine-γ-lyase(CSE) catalysis in the body,It is distributed widely in the body.In the body,it participates in expanding blood vessels,inhibiting smooth muscle cell proliferation and so on.And it plays an important role in pulmonary hypertension,endotoxin shock,surgical trauma and various pathological processes of disease.The generation,metabolism,physiological role and relationship with disease of H2S were reviewed in the article.

Key concepts: Cystathionine gamma-lyase, Cystathionine beta synthase, Hydrogen sulfide, Endogeny, Hydrogen sulphide, ATP synthase, Chemistry, Biochemistry

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