2015•The Chinese Journal of Clinical PharmacologyRequires access

Clinical efficacy and safety evaluation of dinoprostone and double balloon catheter for cervical ripening

Zheng Mei-fen

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Abstract

Objective To evaluation the clinical efficacy and safety of dinoprostone and double balloon catheter for cervical ripening.Methods A total of 208 women with Bishop score less than 6 were randomly divided into treatment group(n = 105) and control group(n =103).Patients in treatment group were given double balloon catheter for cervical ripening,and patients in control group were given dinoprostone for cervical ripening.The data of vaginal delivery in 24 hours,clinical efficacy and incidence of adverse drug reactions were recorded and compared between the two groups.Results The proportion of women who achieved vaginal delivery in 24 hours was higher in the treatment group than in the control group(68.57% vs 49.51%,P 0.05).There was no difference in cesarean delivery rates between the two groups(23.81%vs 26.21%,P 0.05).Oxytocin and epidural analgesia were administered more frequently in treatment group(P 0.05).Uterine tachysystole or hypertonus occurred more frequently in the control group(P 0.05).Conclusion Double-balloon catheter can improve the for vaginal birth within 24 hours in the treatment of cervical ripening.

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Objective To evaluation the clinical efficacy and safety of dinoprostone and double balloon catheter for cervical ripening.Methods A total of 208 women with Bishop score less than 6 were randomly divided into treatment group(n = 105) and control group(n =103).Patients in treatment group were given double balloon catheter for cervical ripening,and patients in control group were given dinoprostone for cervical ripening.The data of vaginal delivery in 24 hours,clinical efficacy and incidence of adverse drug reactions were recorded and compared between the two groups.Results The proportion of women who achieved vaginal delivery in 24 hours was higher in the treatment group than in the control group(68.57% vs 49.51%,P 0.05).There was no difference in cesarean delivery rates between the two groups(23.81%vs 26.21%,P 0.05).Oxytocin and epidural analgesia were administered more frequently in treatment group(P 0.05).Uterine tachysystole or hypertonus occurred more frequently in the control group(P 0.05).Conclusion Double-balloon catheter can improve the for vaginal birth within 24 hours in the treatment of cervical ripening.

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Available abstract

Objective To evaluation the clinical efficacy and safety of dinoprostone and double balloon catheter for cervical ripening.Methods A total of 208 women with Bishop score less than 6 were randomly divided into treatment group(n = 105) and control group(n =103).Patients in treatment group were given double balloon catheter for cervical ripening,and patients in control group were given dinoprostone for cervical ripening.The data of vaginal delivery in 24 hours,clinical efficacy and incidence of adverse drug reactions were recorded and compared between the two groups.Results The proportion of women who achieved vaginal delivery in 24 hours was higher in the treatment group than in the control group(68.57% vs 49.51%,P 0.05).There was no difference in cesarean delivery rates between the two groups(23.81%vs 26.21%,P 0.05).Oxytocin and epidural analgesia were administered more frequently in treatment group(P 0.05).Uterine tachysystole or hypertonus occurred more frequently in the control group(P 0.05).Conclusion Double-balloon catheter can improve the for vaginal birth within 24 hours in the treatment of cervical ripening.

Key concepts: Medicine, Dinoprostone, Ripening, Vaginal delivery, Clinical efficacy, Balloon catheter, Adverse effect, Catheter

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