Relationgship between pulse pressure and severity of coronary artery disease

Objective To evaluate the relationship between pulse pressure(PP) and the severity of coronary artery stenosis.Methods Three hundred and forty patients who were suspected or diagnosed as coronary artery disease were enrolled.They were divided into normal control group(120 cases),single-vessel lesion group(78 cases),doublevessel lesion group(66 cases) and triple-vessel lesion group(76 cases) according to the number of diseased arteries.And the severity of coronary artery stenosis was evaluated by Gensini score.To compare the relationship of aortic pulse pressure and the severity of coronary artery stenosis among the four groups.Results The aortic pulse pressure was significantly higher in patients with coronary artery disease than that in the normal subjects.Multiple regression analysis indicated that aortic pulse pressure was closely related to the severity of coronary lesions.Conclusion Pulse pressure is an independent risk factor for the severity of coronary artery stenosis,and aotic pulse pressure is a better predictor.