The value of preoperative autoiogous plateletpheresis in idiopathic scoliosis orthomorphia

Objective To investigate the value of preoperative autologous plateletpheresis combined with intraoperative autotransfusion in idiopathic scoliosis orthomorphia.Methods Sixty patients with undergoing idiopathic scoliosis orthomorphia were randomized into three groups(n = 20).Group I received preoperative autologous plateletpheresis combined with intraoperative autotransfusion;groupⅡreceived only intraoperative autotransfusion and groupⅢreceived nothing. Coagulation parameters,hemoglobin and hematocrit values,platelet counts and aggregation were evaluated before the anestheria;and 10 min after plateletpheresis,10 min before the infusion of autologous blood or platelet rich plasma,10 min after infusion,24 and 48 h postoperation,Intra-and post-operation blood loss and blood transfusion requirements were recorded.Results Compared with T_1,Plt and the platelet aggregation of all groups were decreased at T_3,T_4(P0.01).Compared with groupⅠ,the blood coagulation and the platelet aggregation of the groupsⅡandⅢwere inhibited at 24 and 48 h after operation(P0.05),the postoperative blood loss and blood transfusion requirement increased(P 0.01 ).Conclusion Preoperative plateletpheresis combined with intraoperative autotransfusion can ameliorate postoperative blood coagulation and the postoperative platelet aggregation of idiopathic scoliosis patients,and then reduce the postoperative bleeding and minimize the need of blood transfusion.