The variance and significance of blood serum 1,25-dihydroxyvitamin D_3 in type2 diabetes mellitus patients

Objective:To compare the difference of serum 1,25-dihydroxyvitamin D3(1,25(OH)2D3) between type 2 diabetes mellitus patients and normal persons,and to analyze the relationship between vitamin D3 and type 2 diabetes mellitus.Methods:110 patients with type 2 diabetes mellitus were selected as the case group,and 105 healthy people were selected as the control group.ELISA was used for the detection of serum 1,25-dihydroxyvitamin D3.Questionnaire survey was performed,and clinical and biochemical indexes were also detected.Results:There was a significant difference in serum 1,25(OH)2D3 level between the case and control group(P 0.01).There was a significant negative correlation between serum 1,25(OH)2D3 level and fasting blood glucose(rs=-0.696,P 0.01).Conclusion:Serum 1,25(OH)2D3 in the case group was significantly lower than that in the control group.The higher fasting blood glucose,the lower serum 1,25(OH)2D3.