2005•Zhongguo yaolixue tongbaoRequires access
Characteristics of inverse agonist action
Yuan Lin
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Abstract
Inverse agonist is a new type of classification.Different form antagonist that blocks the effect of agonist,inverse agonist produces opposite effect to that of agonist.The characteristics of inverse agonists acting on different receptors including H_2,H_3,μ opioid,adrenergic β, and 5-HT_((1B)) receptors are discussed in this paper.Recent investigation suggested that inverse agonist has potential clinical application.