Assessment of Left Ventricular Systolic and Diastolic Function in Hypertension with Left Ventricular Hypertrophy by Doppler Tissue Imaging

Objective This study was performed to assess the myocardial contractile and relaxant function in hypertension with left ventricular hypertrohy(LVH)in patients by Doppler tissue imaging(DTI).Methods In 20 normal subjects and 26 patients with hypertension and LVH,the motion of interventricular septum(IVS)and left ventricular posterior wall(LVPW)were assessed by DTI.Some parameters such as systolic peak velocity(Vs),early-diastolic and late-diastolic peak velocity(Ve,Va respectively),velocity difference(V)and velocity gradient(VG)between endocardium and epicardium,Ve/Va ratio,isovolumic contraction time and isovolumic relaxation time(IVCT,IVRT respectively)were measured.Results Compared with control group,the wall thickness of IVS and LVPW and LVMI of LVH group was significantly increased,E peak velocity and ratio of E and A of LVH group were significantly decreased(P0.01).The Ve、Ve and VGe of the LVS in LVPW and IVS in LVH group were significantly lower than that of control group(P0.01).Conclusion The DTI can be used to assess the function of left ventricular quickly and sensitively.