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[Adhesion to buccal epithelial cells of Candida albicans isolates from oral lichen planus].

Xin Zeng, Qianming Chen, Minhai Nie, Bing-qi Li

Abstract

OBJECTIVE: To investigate the adhesion to buccal epithelial cells of Candida albicans isolates from erosive oral lichen planus (OLP) and nonerosive OLP, and its role in the development of OLP. METHODS: A total of 112 isolates, comprising healthy control (26), erosive OLP (62) and nonerosive OLP (24), were screened for the adhesion by using buccal epithelial cell (BEC) assay. RESULTS: The adhesion to buccal epithelial cells of the isolates from erosive OLP group was stronger than that of those from healthy control. CONCLUSION: Candida albicans, some isolates with a special virulence attribute may contribute to the occurrence and progression of erosive OLP.

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Key concepts: Oral lichen planus, Buccal administration, Candida albicans, Microbiology, Adhesion, Corpus albicans, Biology, Chemistry