The Clinical Application of One-day Protocol in rCBF SPECT with Acetazolamide Tablet

Aim:To discuss the value of one-day protocol of cerebral blood flow imaging with acetazolamide tablet stress to diagnose early cerebral ischemia. Methods: 99m Tc-ECD SPECT date of regional cerebral blood flow (rCBF) study before and after acetazolamide were performed (2g, oral)on 17 patients diagnosed as ischemic cerebral vascular diseases in one day. Measure the value of pH in artery blood before and after acetazolamide loading, compare the positive rate of three kinds of methods. Results:The value of ph decreased after acetazolamide loading (the t value is 6.426, P0.001,the positive rate of CT、rest test and combined test is 23.5% 29.4% and 70.6% respectively. There is significant difference in positive rate of CT and combine test (χ 2=6.125,P0.01).Conclusion:One-day protocol acetazalomide tablet test is safe, stress test can increase positive rate in cerebral ischemia.