2005Zhejiang Journal of Integrated Traditional Chinese and Western MedicineRequires access

Clinical Research of Fufangbiejiaruangan Tablet Combined with γ-Interferon on Treating Hepatic Fibrosis

Lijian Chen

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Abstract

Objective: To explore the curative effect of Fufangbiejiaruangan tablets combined with γ-interferon on treating hepatic fibrosis. Methods:49 cases with chronic hepatitis B were divided randomly into treatment group (28 cases) and contrast group (21 cases). The treatment group was treated by γ-interferon with 1000000 U every day in first two months, then with 1000000 U every other day,combined with 12 Fufangbiejiaruangan tablets orally every day. The contrast group was treated by the same dose of γ-interferon only. After 6 months of therapy, indices including liver histology, liver function, liver fibrosis and B ultrasonic were tested and compared. Results: Indices of both groups after treatment were improved obviously compared with those before treatment. The clinical effect of treatment group was significantly better than that of contrast group. Conclusion: The clinical effect of Fufangbiejiaruangan tablets combined with γ-interferon on treating hepatic fibrosis is better than that of γ-interferon only.

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What this paper is about

Objective: To explore the curative effect of Fufangbiejiaruangan tablets combined with γ-interferon on treating hepatic fibrosis. Methods:49 cases with chronic hepatitis B were divided randomly into treatment group (28 cases) and contrast group (21 cases). The treatment group was treated by γ-interferon with 1000000 U every day in first two months, then with 1000000 U every other day,combined with 12 Fufangbiejiaruangan tablets orally every day. The contrast group was treated by the same dose of γ-interferon only. After 6 months of therapy, indices including liver histology, liver function, liver fibrosis and B ultrasonic were tested and compared. Results: Indices of both groups after treatment were improved obviously compared with those before treatment. The clinical effect of treatment group was significantly better than that of contrast group. Conclusion: The clinical effect of Fufangbiejiaruangan tablets combined with γ-interferon on treating hepatic fibrosis is better than that of γ-interferon only.

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Available abstract

Objective: To explore the curative effect of Fufangbiejiaruangan tablets combined with γ-interferon on treating hepatic fibrosis. Methods:49 cases with chronic hepatitis B were divided randomly into treatment group (28 cases) and contrast group (21 cases). The treatment group was treated by γ-interferon with 1000000 U every day in first two months, then with 1000000 U every other day,combined with 12 Fufangbiejiaruangan tablets orally every day. The contrast group was treated by the same dose of γ-interferon only. After 6 months of therapy, indices including liver histology, liver function, liver fibrosis and B ultrasonic were tested and compared. Results: Indices of both groups after treatment were improved obviously compared with those before treatment. The clinical effect of treatment group was significantly better than that of contrast group. Conclusion: The clinical effect of Fufangbiejiaruangan tablets combined with γ-interferon on treating hepatic fibrosis is better than that of γ-interferon only.

Key concepts: Medicine, Interferon, Gastroenterology, Internal medicine, Chronic hepatitis, Fibrosis, Hepatic fibrosis, Liver fibrosis

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