Surveillance on drug resistance of 357 strains escherichia coli in recent three years

Aim To study the resistance and its tendency of E.coli to antibiotics and ESBLs-producing analysis in recent three years.Methods Drug susceptibility test and double disc synergy test were employed to analyze the drug sensitivities of 357 strains clinical isolated E.coli from 2004 to 2006 in Susong People's Hospital.Results The resistance rates of E.coli to ampicillin,ciprofloxacin levofloxacin exceeded 50%,and they were about 40% to cefuroxime,cefotaxime,ceftriaxone,ceftazidime,aztreonam,gentamicin,amikacin.In addition,the resistant rates were about 20% to piperacillin/tazobactam,cefoxitin,cefepime,there was no resistance to imipenem and meropenem.The detection rates of ESBLs to E.coli was 36.5%,38.7%,and 41.6% in 2004,2005,2006 respectively.Conclusions The resistance rates of E.coli to antibiotics and the rates of ESBLs-producing ascended year by year.More attention should be paid to the detection of drug resistance strains and antibiotics should be used rationally and regularly.