2001•Journa of Henan Medical UniversityRequires access

Flow cytometry used in the immunophenotype in adult acute leukemia

Zou Dianbin

Abstract

Aim:To study antigen expression characteristic of acute leukemia(AL) immunophenotype by FCM and clinical significance.Methods: Fourteen patients with AL were investigated with MoAb and immunofluorescence.Results: Five cases were characteristic of double lineage expression,namely two lineage antigen expression simultaneously(AML 3 cases,ALL 2 cases);9 cases were characteristic of one lineage expression(AML 5 cases,ALL 4 cases).Conclusion: ALL with double lineage expression is related to poor prognosis;FCM have a characteristic of detecting large quantity of cells,rapidness and accuracy.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Immunophenotyping, Lineage (genetic), Flow cytometry, Acute leukemia, Leukemia, Antigen, Immunofluorescence, Cell lineage