2004•Unpublished venueRequires access

Effects of Gonghuanzhixue Tablets on Contraction Activity of Rats Uterine Smooth Muscle in Vitro

FU Ling-mei

Abstract

Objective To explore the mechanism of Gonghuanzhixue Tablets for treating endometrorrhagia caused by copper intrauterine device (Cu-IUD). Methods In constrast withpregnendione and oxytocin, we investigated contraction activity of rats uterine smooth muscle by LMS two-path physiological recorder and JH-2 muscular tension transmitte. Results Gonghuanzhixue Tablets could enhance the activity of rats uterine smooth muscle, but have apparent counteraction to the fierce contraction activity of uterine smooth muscle caused by oxytocin. Conclusion Gonghuanzhixue Tablets can bidirectional regulate the contractility of uterine smooth muscle and ameliorate the pathologic status of uterine smooth muscle so as to hemostatic.

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Key concepts: Oxytocin, Uterine contraction, Contraction (grammar), Smooth muscle, Contractility, Uterus, Muscle contraction, Internal medicine