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Synthesis and Fungicidal Activity of N-(5-Aryl-1,3,4-thiadiazol-2-yl)-N′-α-Naphthylacetylthioureas

Qin Zhang-lan

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Abstract

A series of novel N-(5-aryl-1,3,4-oxadiazol-2-yl)-N′-α-naphthylacetylthioureas were synthesized from 2-amino-5-aryl-1,3,4-oxadiazoles. Their structures had been confirmed by IR, MS,()~1H NMR and elemental analysis. The results of biological test showed that most of these (compounds) had good fungicidal activity. The fungicidal activity to Botrytis cinereapers, could mostly reach 80%.

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A series of novel N-(5-aryl-1,3,4-oxadiazol-2-yl)-N′-α-naphthylacetylthioureas were synthesized from 2-amino-5-aryl-1,3,4-oxadiazoles. Their structures had been confirmed by IR, MS,()~1H NMR and elemental analysis. The results of biological test showed that most of these (compounds) had good fungicidal activity. The fungicidal activity to Botrytis cinereapers, could mostly reach 80%.

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Available abstract

A series of novel N-(5-aryl-1,3,4-oxadiazol-2-yl)-N′-α-naphthylacetylthioureas were synthesized from 2-amino-5-aryl-1,3,4-oxadiazoles. Their structures had been confirmed by IR, MS,()~1H NMR and elemental analysis. The results of biological test showed that most of these (compounds) had good fungicidal activity. The fungicidal activity to Botrytis cinereapers, could mostly reach 80%.

Key concepts: Aryl, Chemistry, Botrytis cinerea, Proton NMR, Fungicide, Elemental analysis, Botrytis, Medicinal chemistry

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Synthesis and Fungicidal Activity of N-(5-Aryl-1,3,4-thiadiazol-2-yl)-N′-α-Naphthylacetylthioureas — Research Paper | ScholarLens