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2006•China Journal of Oral and Maxillofacial SurgeryRequires access

Central mucoepidermoid carcinoma of the mandible :Report of 3 cases

Jiang Wei Xiao

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Abstract

PURPOSE: To investigate the diagnosis and treatment of central mucoepidermoid carcinoma of the jaws by clinical analysis. METHODS: This paper presented 3 cases of CMCJ treated in our hospital from 1995 to 2005. Their clinical data, therapies and prognosis were analyzed retrospectively. RESULTS: The major clinical manifestations of the 3 cases of CMCJ included gradual enlargement of the jaw, paresthesia, pain and repeated bleeding. After operation, 2 out of 3 cases had local recurrences, with the longest interval up to 3 years. The recurrence may be related to conservative resection of the tumor. After a second operation of hemimandibulectomy, none of the 2 cases had recurrence or metastasis. CONCLUSIONS: Correct preoperative diagnosis and close follow- up may contribute to the early diagnosis and proper treatment of central mucoepidermoid carcinoma of jaws. The extent of local resection remains one of the main factors that affect prognosis.

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PURPOSE: To investigate the diagnosis and treatment of central mucoepidermoid carcinoma of the jaws by clinical analysis. METHODS: This paper presented 3 cases of CMCJ treated in our hospital from 1995 to 2005. Their clinical data, therapies and prognosis were analyzed retrospectively. RESULTS: The major clinical manifestations of the 3 cases of CMCJ included gradual enlargement of the jaw, paresthesia, pain and repeated bleeding. After operation, 2 out of 3 cases had local recurrences, with the longest interval up to 3 years. The recurrence may be related to conservative resection of the tumor. After a second operation of hemimandibulectomy, none of the 2 cases had recurrence or metastasis. CONCLUSIONS: Correct preoperative diagnosis and close follow- up may contribute to the early diagnosis and proper treatment of central mucoepidermoid carcinoma of jaws. The extent of local resection remains one of the main factors that affect prognosis.

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Available abstract

PURPOSE: To investigate the diagnosis and treatment of central mucoepidermoid carcinoma of the jaws by clinical analysis. METHODS: This paper presented 3 cases of CMCJ treated in our hospital from 1995 to 2005. Their clinical data, therapies and prognosis were analyzed retrospectively. RESULTS: The major clinical manifestations of the 3 cases of CMCJ included gradual enlargement of the jaw, paresthesia, pain and repeated bleeding. After operation, 2 out of 3 cases had local recurrences, with the longest interval up to 3 years. The recurrence may be related to conservative resection of the tumor. After a second operation of hemimandibulectomy, none of the 2 cases had recurrence or metastasis. CONCLUSIONS: Correct preoperative diagnosis and close follow- up may contribute to the early diagnosis and proper treatment of central mucoepidermoid carcinoma of jaws. The extent of local resection remains one of the main factors that affect prognosis.

Key concepts: Mucoepidermoid carcinoma, Medicine, Distant metastasis, Mandible (arthropod mouthpart), Resection, Conservative treatment, Surgery, Carcinoma

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